Hepatopulmonary Syndrome in a Nigerian Man with Decompensated Alcoholic Liver Cirrhosis
نویسندگان
چکیده
Hepatopulmonary syndrome is a rare complication of liver disease and portal hypertension. It has not been previously described in medical literature Nigeria. We report this case 64-year-old man who presented with 3 months’ history recurrent breathlessness, platypnoea leg swelling. He had diagnosed cirrhosis variceal band ligation 2018, managed for 2 episodes hepatic encephalopathy prior to referral. Physical examination showed he was respiratory distress, centrally cyanosed, grade 4 digital clubbing, tachypnoea, platypnoea, orthodeoxia bibasal coarse crepitations also non-tender hepatomegaly, splenomegaly ascites no edema. Investigations negative screening hepatitis B C, elevated AST GGT, conjugated hyperbilirubinemia, hypoalbuminemia, COVID-19 test, polycythemia, thrombocytopenia, prolonged INR enlarged irregular margins on ultrasound. Gastroscopy revealed Grade oesophageal varices, Forrest pre-pyloric ulcer hypertensive gastropathy. Spirometry demonstrated restrictive pattern airflow limitation. Contrast echocardiography intrapulmonary shunt. Alpha-1- anti-trypsin deficient. The peripheral cyanosis resolved oxygen therapy. initially commenced pentoxyfylline but terminated therapy due side effects.
 relevant reviewed. Liver transplantation the only effective HPS prompt recognition referral transplant key.
 therefore present first documented published hepatopulmonary Nigeria West African sub-region.
منابع مشابه
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متن کامل
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Hepatopulmonary syndrome (HPS) is a complication of liver disease. It is most frequently related to portal hypertension (with or without cirrhosis), although chronic liver disease of almost any etiology could be related to HPS (1, 2). Moreover, some acute liver diseases are related to HPS, such as ischemic hepatitis (3). HPS can be diagnosed when the following disorders have been approved (1, 4...
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ژورنال
عنوان ژورنال: Journal of advances in medicine and medical research
سال: 2022
ISSN: ['2456-8899']
DOI: https://doi.org/10.9734/jammr/2022/v34i234842